Unfortunately, Fallout New Vegas is a game that suffers from frequent crashes, especially if you heavily mod it.
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You’ll want to download the New Vegas Script Extender, which will expand the game’s script, allowing you to install far more mods. The Nexus Mod Manager is a great modding tool that allows you to handily store all your mods in one place, and also ensure that your mods are loaded in the correct order.
Oh, and if you use NVEC, it's a known bug with one of the integrated weapon packs, the Nordic weapons, where the meshes are named incorrectly. Disable and re-enable archiveinvalidation.